Advanced Wrinkle Reduction Without Injections

Our revolutionary Notox™ Botox-Effect Serum visibly reduces fine lines and wrinkles while progressively strengthening skin structure for lasting results. This breakthrough formula delivers immediate smoothing benefits while progressively enhancing the skin’s natural collagen production with each application.

Beyond Ordinary Anti-Aging Serums

Unlike conventional anti-aging serums that rely on simple hydration or temporary plumping effects, our Notox™ Botox-Effect Serum works at the cellular level through our exclusive NeuroSmooth™ Complex. This proprietary system combines neuropeptide technology with botanical muscle-relaxing actives to visibly reduce expression lines while simultaneously reinforcing long-term skin structure.

The result is not the temporary tightening of traditional serums, but a genuine relaxation of facial tension with exceptional wrinkle-reducing benefits—the difference between masking wrinkles and actually diminishing their appearance.

Science-Driven Formula

Our meticulously balanced formula features advanced peptide technology that targets expression lines without compromising natural facial movement. Our precisely calibrated blend of plant-based muscle relaxants work in harmony with the skin’s natural processes while our time-release system ensures continuous benefits throughout the day.

COSMOS NATURAL Certified

Proudly carrying the prestigious COSMOS NATURAL certification, our Notox™ Botox-Effect Serum delivers professional-level results while adhering to the highest standards of natural formulation. Free from silicones, synthetic fragrances, parabens, and artificial preservatives, this serum creates authentic, healthy rejuvenation rather than temporary artificial effects.

Immediate & Progressive Benefits

From the first application, experience the transformation as fine lines appear instantly softened, skin feels smoother, and facial tension visibly relaxes without the frozen look of injections. With continued use, our formula progressively strengthens the skin’s natural collagen and elastin networks—rebuilding structural support for increasingly firm, youthful skin that maintains natural expressiveness.

Universal Age-Defying Care

Meticulously tested across various skin types and concerns, our Notox™ Botox-Effect Serum delivers exceptional results for normal, dry, sensitive, combination, and mature skin. The lightweight formula provides potent wrinkle-reducing benefits without congesting pores, while offering enough treatment actives to visibly improve even deep-set expression lines.

Experience The Transformation

Transform your anti-aging skincare routine with our Notox™ Botox-Effect Serum and discover the extraordinary difference between temporarily masking wrinkles and genuinely reducing their appearance. Enjoy visibly smoother, more relaxed-looking skin that maintains natural expression and radiates with youthful vitality, without needles or downtime.

For optimal results, use as part of a complete anti-aging skincare routine.

The Revolutionary Science Behind Notox™ Botox-Effect Serum

At the heart of our Notox™ Botox-Effect Serum lies our exclusive NeuroSmooth™ Complex—a breakthrough innovation in skincare science that transforms conventional anti-aging treatments into a powerful wrinkle-reduction system without injections. This proprietary formulation represents the culmination of years of research into neuromuscular mechanisms that contribute to expression lines and wrinkles.

The Science of Expression Lines

Facial wrinkles develop through a combination of factors, with repeated muscle contractions being a primary contributor to expression lines around the eyes, forehead, and mouth. Traditional injectable treatments work by temporarily paralyzing these muscles, while most topical products simply hydrate or plump the skin surface without addressing muscle-related wrinkle formation.

Our NeuroSmooth™ Complex takes a different approach by:

  1. Targeting Neuromuscular Junctions: The specialized neuropeptides in our formula help modulate muscle contractions at the cellular level, visibly relaxing tension patterns that contribute to wrinkle formation.
  2. Supporting Dermal Structure: Rather than just relaxing muscles, NeuroSmooth™ actively strengthens the skin’s underlying support systems through collagen-boosting technology.
  3. Reinforcing Skin Resilience: The complex helps improve skin’s elasticity and bounce-back capability, supporting long-term resistance to wrinkle formation.
  4. Creating Progressive Improvement: With each application, NeuroSmooth™ compounds its rejuvenating effects, gradually enhancing your skin’s natural smoothness and firmness over time.

Key Components of NeuroSmooth™ Complex

Advanced Neuropeptide System

At the core of our NeuroSmooth™ Complex is our revolutionary peptide technology, featuring carefully selected ingredients that work with your skin’s natural mechanisms:

  • Acetyl Hexapeptide-8: This specialized peptide works to modulate muscle contraction signals, visibly relaxing tension in expression areas without paralyzing facial movement.
  • Pentapeptide-18: Works synergistically with other peptides to soften the appearance of expression lines and prevent new wrinkle formation.
  • Dipeptide Diaminobutyroyl Benzylamide Diacetate: Helps inhibit muscle contraction mechanisms while maintaining natural facial expressiveness.
  • Palmitoyl Tripeptide-38: Supports all skin layers with structural rebuilding benefits for comprehensive wrinkle reduction.

Botanical Muscle Relaxants

Our formula includes a powerful blend of plant extracts with natural muscle-relaxing properties:

  • Hibiscus Extract: Contains natural muscle-relaxing properties that help smooth the appearance of fine lines and wrinkles.
  • Acmella Oleracea Extract: Known as “nature’s Botox,” this plant extract helps relax facial muscles for a smoother appearance.
  • Alga Extract: Provides relaxing properties while delivering minerals that support overall skin health.
  • Gardenia Stem Cells: Helps reinforce skin structure while providing natural tension-relieving benefits.

Collagen-Boosting Technology

Our exclusive regenerative system strengthens skin’s natural support structures:

  • Retinol Alternative Complex: Derived from bakuchiol and botanical extracts, this gentle yet effective system stimulates collagen production without irritation.
  • Hyaluronic Acid Complex: Multi-molecular weight hyaluronic acid penetrates different skin layers for comprehensive volume support.
  • Vitamin C Derivatives: Stable, non-irritating forms of vitamin C that boost collagen synthesis while brightening skin tone.
  • Peptide-Rich Algae Extract: Marine-derived ingredients that help accelerate skin’s natural collagen production.

Advanced Delivery System

The NeuroSmooth™ Complex operates on an innovative multi-layer delivery mechanism:

  1. The Surface Phase: Instantly delivers smoothing ingredients to visibly soften fine lines.
  2. The Epidermal Phase: Gradually releases muscle-relaxing actives to reduce expression line formation.
  3. The Dermal Phase: Delivers collagen-boosting ingredients to the skin’s structural layers.

This multi-dimensional approach ensures comprehensive wrinkle reduction that addresses both immediate appearance and long-term causes of aging.

COSMOS NATURAL Certified

Like all components of our skincare systems, our NeuroSmooth™ Complex adheres to the strict standards of COSMOS NATURAL certification. All ingredients are naturally derived and sustainably sourced, with no synthetic peptide mimics, harmful preservatives, or laboratory-created compounds.

This commitment to clean, green formulation ensures that your skin receives only the purest, most beneficial ingredients, creating authentic results that improve with continued use.

The NeuroSmooth™ Difference

The revolutionary NeuroSmooth™ Complex in our Notox™ Botox-Effect Serum represents a fundamental advancement in non-invasive wrinkle reduction. Unlike traditional approaches that simply mask lines or temporarily inflate the skin surface, our complex works in harmony with your skin’s natural processes to create genuine, lasting smoothness.

Experience the transformation for yourself and discover how our proprietary complex can unlock your skin’s true rejuvenation potential, creating visibly smoother, more youthful skin without sacrificing natural expressiveness.

How to Use Notox™ Botox-Effect Serum: Optimal Usage Guide

Achieving that coveted wrinkle-free appearance isn’t just about using the right products—it’s about using them correctly. Our Notox™ Botox-Effect Serum has been formulated with cutting-edge NeuroSmooth™ Complex to deliver impressive wrinkle reduction, but following the proper techniques will ensure you get the most dramatic results possible. This comprehensive guide will walk you through the ideal usage routine and explain how various factors can affect your results.

Optimal Usage Instructions

Pre-Application Preparation

  1. Cleanse Thoroughly: Start with clean skin using a gentle cleanser that won’t strip your skin’s natural moisture barrier or leave residue that could impede serum absorption.
  2. Exfoliate Regularly: 2-3 times weekly, use a gentle exfoliant to remove dead skin cells that can prevent optimal penetration of active ingredients.
  3. Apply to Slightly Damp Skin: For enhanced absorption, apply Notox™ to skin that is slightly damp from toning or facial mist, which helps the hyaluronic acid components lock in maximum hydration.

Proper Application Technique

  1. Amount Matters: Dispense approximately a pea-sized amount (about 2-3 drops) of Notox™ Botox-Effect Serum onto fingertips.
  2. Target Expression Lines First: Apply a small amount directly to areas with the most pronounced expression lines—typically the forehead, between eyebrows, and around the eyes and mouth.
  3. Use Gentle Pressure: Apply using your ring finger (which naturally applies less pressure) with light tapping motions rather than rubbing, which can create friction that counteracts the relaxing effect.
  4. Press and Release: Use a press-and-release motion on expression areas to help the peptides penetrate without creating additional tension in the facial muscles.
  5. Optimal Duration: Allow the serum to absorb for 30-60 seconds before applying additional products. This gives the NeuroSmooth™ Complex time to begin interacting with skin’s neuromuscular function.

Facial Massage Technique

  1. Smooth Upward: After applying the serum, use gentle upward strokes from the center of the face outward to enhance circulation without creating additional tension.
  2. Focus on Tension Points: Lightly press and hold at points where you typically hold tension, such as the “11 lines” between brows, for 3-5 seconds each.
  3. Avoid Excess Manipulation: Keep massage brief (30-60 seconds total) as over-manipulation can counteract the muscle-relaxing benefits of the formula.

Post-Application Care

  1. Layer Correctly: Wait 30-60 seconds before applying moisturizer or other treatments to ensure maximum penetration of active ingredients.
  2. Apply Sunscreen Daily: Always follow morning applications with broad-spectrum SPF 30+ protection to prevent UV damage that can counteract anti-aging benefits.
  3. Avoid Excessive Facial Movement: For 5-10 minutes after application, try to maintain a neutral facial expression to allow the muscle-relaxing peptides to properly interact with expression areas.

Frequency Guidelines

Optimal Application Schedule

  • Normal/Combination Skin: Apply twice daily, morning and evening
  • Dry/Mature Skin: Apply twice daily, with a slightly larger amount in the evening
  • Sensitive Skin: Begin with evening application only, gradually increasing to twice daily as tolerance builds
  • Oily Skin: Apply once daily, preferably in the evening after thorough cleansing

Progressive Results Timeline

  • First Use: Immediate smoothing effect, temporary softening of fine lines, enhanced skin hydration
  • After One Week: Noticeable reduction in appearance of fine lines, beginning relaxation of expression lines
  • After Two Weeks: Visible improvement in skin firmness, significant softening of expression lines
  • After Four Weeks: Dramatic reduction in wrinkle depth and appearance, improved skin elasticity and overall younger appearance

Factors That Affect Results

Expression Habits Considerations

Facial expressions can significantly impact how effectively our Notox™ Botox-Effect Serum works:

  • Repetitive Expressions: Constantly furrowing brows, squinting, or pursing lips can counteract the benefits of muscle-relaxing peptides
  • Sleeping Positions: Side or stomach sleeping can create “sleep wrinkles” that become harder to treat

Solutions for Expression Habit Issues:

  1. Mindfulness Practice: Develop awareness of tension-holding patterns and practice consciously relaxing facial muscles throughout the day
  2. Sleep Position Training: Try training yourself to sleep on your back using special pillows designed for this purpose
  3. Facial Yoga: Incorporate strategic facial exercises designed to strengthen supporting muscles while relaxing tension-prone areas

Skin Type and Condition

Different skin types require slight adjustments to achieve optimal results:

Dry Skin:

  • Apply a hydrating toner before Notox™ to enhance penetration
  • Consider layering with facial oil after serum application for additional moisture barrier support
  • May benefit from slightly larger amount of product, especially in drier areas

Oily/Combination Skin:

  • Use oil-free hydrators in conjunction with Notox™
  • Apply slightly less product to avoid potential congestion
  • Focus application on specific expression lines rather than full-face coverage

Sensitive Skin:

  • Patch test before full application
  • Begin with evening-only application, gradually increasing frequency
  • Consider refrigerating the product to enhance the soothing effect

Mature Skin:

  • Incorporate gentle facial massage during application to enhance circulation
  • Layer with hyaluronic acid serums for enhanced hydration
  • May require a full 4-week cycle for dramatic results

Environmental Factors

Environmental conditions can affect your results:

Climate:

  • In dry environments, layer with additional hydration products
  • In humid conditions, the serum may be sufficient without additional hydration
  • Consider using more product during seasonal transitions when skin is adjusting

Pollution Exposure:

  • Double cleanse in the evening to remove airborne pollutants before applying
  • Consider applying antioxidant serum before Notox™ in high-pollution environments
  • Enhance nighttime application to support skin’s natural repair processes

Sun Exposure:

  • Always apply SPF after morning application
  • Consider increased evening application after significant sun exposure
  • Use additional sun protection measures (hats, sunglasses) to prevent expression lines caused by squinting

Skincare Integration

How you incorporate Notox™ Botox-Effect Serum into your routine affects results:

Morning Routine:

  • Apply after cleansing and toning but before moisturizer and sunscreen
  • Wait 30-60 seconds between layers to ensure maximum absorption
  • Use gentle pressing motions rather than rubbing when applying subsequent products

Evening Routine:

  • Apply after cleansing, toning, and any treatment essences
  • Can be layered with other treatment serums (apply thinnest to thickest)
  • Apply before heavier night creams or facial oils

Weekly Treatments:

  • Use after exfoliation treatments for enhanced penetration
  • Can be incorporated with sheet masks by applying before mask application
  • Apply after at-home facial steaming for maximum absorption

Troubleshooting Common Issues

Insufficient Results

If you’re experiencing less dramatic results than expected:

  1. Check Application Amount: Too little product may not deliver sufficient active ingredients
  2. Review Application Frequency: Consistent twice-daily application typically yields best results
  3. Evaluate Facial Tension Habits: Be mindful of unconscious facial expressions that counteract relaxing effects

Pilling or Rolling

If the product pills or rolls on the skin:

  1. Allow Previous Products to Fully Absorb: Wait longer between skincare steps
  2. Use Less Product: A pea-sized amount is typically sufficient
  3. Pat Rather Than Rub: Change application technique to gentle pressing motions

Temporary Sensitivity

If you experience mild tingling or sensitivity:

  1. Reduce Frequency: Scale back to once-daily application temporarily
  2. Check Exfoliation Routine: Over-exfoliation can increase sensitivity to active ingredients
  3. Simplify Routine: Remove potential irritants from routine until sensitivity subsides

Special Applications

Special Occasion Preparation

For event preparation or maximum results:

  1. Intensive Treatment Week: Use twice daily plus an additional mid-day application for 5-7 days before special events
  2. Combine with Facial Massage: Add 60-second facial massage focusing on expression areas
  3. Boost with Sheet Mask: Apply Notox™, then cover with a hydrating sheet mask for 15-20 minutes

Targeted Treatment Areas

For especially challenging areas:

  1. Concentrated Application: Apply a slightly larger amount to persistent wrinkles, allowing longer absorption time
  2. Targeted Pressure Points: Use fingertips to press product into deeper wrinkles for 3-5 seconds
  3. Layer Application: For very deep wrinkles, apply a first layer, allow to absorb completely, then follow with a second layer

Conclusion

The key to achieving and maintaining that coveted smooth, wrinkle-free appearance is consistency in your routine and understanding how different factors affect your results. By following these guidelines and adjusting based on your individual skin type, expression habits, and environmental conditions, you’ll maximise the extraordinary wrinkle-reducing potential of our Notox™ Botox-Effect Serum.

Remember that true, lasting wrinkle reduction comes from consistent application and mindful facial habits, so be patient and give the NeuroSmooth™ Complex time to work its transformative magic. With proper use, the results will speak for themselves—visibly smoother, more youthful skin without needles or downtime.

The Science Behind Our Notox™ Botox-Effect Serum Ingredients

Our Notox™ Botox-Effect Serum isn’t just another anti-aging product—it’s a scientifically formulated blend of premium ingredients designed to visibly reduce expression lines and wrinkles. Each ingredient has been carefully selected for its specific skin benefits, working in harmony with our NeuroSmooth™ Complex to create smoother, more youthful-looking skin without injections.

Key Active Ingredients

Neuropeptide Technology: The Expression Line Reducers

At the heart of our Notox™ Botox-Effect Serum is our advanced peptide technology, which visibly relaxes facial tension:

  • Acetyl Hexapeptide-8: Often called “Argireline,” this peptide helps reduce the appearance of expression lines by modulating muscle contractions in a manner similar to botulinum toxin, but without injections or “frozen” appearance.
  • Pentapeptide-18: Works synergistically with other peptides to visibly smooth expression lines around the eyes and forehead by helping to inhibit muscle contraction.
  • Dipeptide Diaminobutyroyl Benzylamide Diacetate: This advanced peptide helps relax facial muscles and smooth wrinkles while maintaining natural facial expressions.
  • Palmitoyl Tripeptide-38: Stimulates the production of six major components of skin matrix (collagen I, III, IV, fibronectin, hyaluronic acid and laminin 5) for comprehensive structural improvement.

Botanical Muscle Relaxants: The Natural Tension Relievers

Our specialised botanical blend provides immediate and long-term tension-relieving benefits:

  • Hibiscus Extract: Rich in AHAs and antioxidants, hibiscus naturally helps relax muscles while providing gentle exfoliation for smoother skin.
  • Acmella Oleracea Extract: Known as “nature’s Botox,” this plant extract contains spilanthol that helps relax facial muscles to reduce the appearance of expression lines.
  • Alga Extract: Marine-derived ingredients that help tone and tighten skin while providing natural muscle-relaxing properties.
  • Gardenia Stem Cells: Help reinforce skin structure while providing natural tension-relieving benefits and antioxidant protection.

Structural Support System: The Collagen Boosters

Our exclusive regenerative complex strengthens skin’s natural support network:

  • Bakuchiol: A gentle, natural alternative to retinol that stimulates collagen production and cell turnover without irritation or sun sensitivity.
  • Vitamin C Derivatives: Stable forms of vitamin C that boost collagen synthesis while brightening skin tone and providing antioxidant protection.
  • Hyaluronic Acid Complex: Multi-weight hyaluronic molecules that hydrate different layers of the skin, instantly plumping fine lines while supporting long-term hydration.
  • Peptide-Rich Algae Extract: Marine-derived ingredients that help accelerate skin’s natural collagen and elastin production.

Supporting Ingredients

Hydration Optimisers

Our advanced hydration system ensures optimal moisture levels:

  • Sodium Hyaluronate: A smaller form of hyaluronic acid that penetrates deeply to hydrate from within.
  • Glycerin: A humectant that attracts and retains moisture in the skin.
  • Panthenol: Vitamin B5 derivative that soothes and hydrates while improving skin barrier function.

Antioxidant Protection

Our specialised antioxidant blend fights free radical damage:

  • Vitamin E: Provides powerful antioxidant protection while supporting skin healing.
  • Green Tea Extract: Rich in polyphenols that protect against environmental damage while soothing skin.
  • Ferulic Acid: Enhances the effectiveness of other antioxidants while providing its own protective benefits.
  • Niacinamide: Vitamin B3 that strengthens the skin barrier, reduces redness, and improves texture.

Soothing Agents

Our calming botanical blend reduces irritation and redness:

  • Chamomile Extract: Soothes sensitive skin and reduces redness while providing anti-inflammatory benefits.
  • Aloe Vera: Calms irritation while delivering hydration and supporting skin repair.
  • Allantoin: Promotes cell regeneration while soothing and protecting delicate skin.

The Advanced Delivery Formula

Our Notox™ Botox-Effect Serum is carefully formulated to maximise ingredient efficacy:

  • Liposomal Delivery System: Encapsulates active ingredients in lipid shells for deeper penetration and time-released benefits.
  • Multi-Weight Molecular Structure: Different molecular weights ensure ingredients reach their optimal skin layer for maximum effectiveness.
  • pH-Optimized Formula: Balanced pH ensures ingredients remain stable and effective while respecting skin’s natural acid mantle.

Free From Harmful Ingredients

What’s not in our formula is just as important as what is:

  • Silicone-Free: No dimethicone or cyclomethicone that can trap impurities and prevent actives from penetrating.
  • Synthetic Fragrance-Free: No artificial fragrances that can trigger irritation and sensitivity.
  • Paraben-Free: Contains no methylparaben, propylparaben, or other preservatives that may disrupt hormonal balance.
  • Artificial Color-Free: Free from synthetic dyes that can cause irritation or allergic reactions.
  • Cruelty-Free: Never tested on animals, reflecting our commitment to ethical beauty.

The Synergistic Effect

While each ingredient in our Notox™ Botox-Effect Serum offers impressive benefits individually, the true magic happens when they work together:

  1. The Neuropeptides relax muscle tension that contributes to expression lines.
  2. The Botanical Relaxants provide natural muscle-relaxing benefits without harshness.
  3. The Collagen Boosters strengthen skin’s underlying support structure.
  4. The Hydration Optimizers plump and smooth the skin surface.
  5. The Antioxidant Protection prevents future damage that accelerates aging.

Together, these ingredients create a synergistic system that visibly reduces wrinkles and expression lines, strengthens skin structure, and prevents new lines from forming with each application.

Complete Ingredients List

Aqua/Water/Eau – Purified base for the formula

Glycerin – Natural humectant for hydration

Acetyl Hexapeptide-8 – Expression line-reducing peptide

Pentapeptide-18 – Wrinkle-relaxing peptide

Dipeptide Diaminobutyroyl Benzylamide Diacetate – Muscle-relaxing peptide

Palmitoyl Tripeptide-38 – Structural support peptide

Hibiscus Extract – Natural muscle-relaxing botanical

Acmella Oleracea Extract – “Nature’s Botox” plant extract

Alga Extract – Marine-derived tension reliever

Gardenia Stem Cells – Regenerative botanical active

Bakuchiol – Natural retinol alternative

Sodium Ascorbyl Phosphate – Stable vitamin C derivative

Sodium Hyaluronate – Penetrating hyaluronic acid form

Panthenol – Vitamin B5 for soothing and hydration

Tocopheryl Acetate – Vitamin E for antioxidant protection

Camellia Sinensis (Green Tea) Leaf Extract – Protective antioxidant

Ferulic Acid – Antioxidant potentiator

Niacinamide – Vitamin B3 for barrier support

Chamomilla Recutita (Matricaria) Flower Extract – Soothing botanical

Aloe Barbadensis Leaf Juice – Calming and hydrating ingredient

Allantoin – Cell regeneration supporter

Xanthan Gum – Natural thickener

Sodium Phytate – Natural preservative enhancer

Sodium Benzoate – Natural preservative

Potassium Sorbate – Natural preservative

Citric Acid – pH adjuster

All ingredients are vegan, cruelty-free, and COSMOS NATURAL certified. Formulated without silicones, synthetic fragrances, parabens, artificial colors, or petroleum derivatives.